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. 2016 May 30;213(6):1061–1077. doi: 10.1084/jem.20151025

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© 2016 Blohmke et al.

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Figure 3. — Plasma cytokine profiles within hours after challenge. Cytokine induction [log₂ FC/D0] at prechallenge (D0), 12, 24, and 48 h after challenge in participants who were diagnosed (n = 25, dark gray) or stayed well (n = 16, light gray) after challenge with S. Typhi (A). Cytokine induction [log₂ FC/D0] at 12 h, 24 h after ingestion of sodium bicarbonate solution (n = 10; B). Data are median with 25th/75th percentile and run in duplicates. **, P < 0.01; ****, P < 0.0001; using unpaired Student’s t test (Table S4).