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Splenic weight as well as splenic length (not shown) significantly increased in dibutyltin dichloride-treated animals (P < 0.01). In contrast thymic weight decreased in dibutyltin dichloride-treated (DBTC) vs the sham-treated (sham) animals (P < 0.001) due to atrophy and depletion of lymphocytes and thymocytes. n = 8 animals/group.
