Serum amylase (A) and activity of lung myeloperoxidase (B). Numbers of cases from each group statistically analyzed are 12 (Normal control), 9 (SAP 24 h), 8 (SAP 48 h), 8 (SAP 72 h), 8 (PBS) and 12 (rIL-22). Results are presented as mean ± SD. aP < 0.05 vs the normal control group, cP < 0.05 vs the SAP group at 72 h. SAP: Acute severe pancreatitis; MPO: Myeloperoxidase; PBS: Phosphate-buffered saline; rIL-22: Recombinant interleukin-22.