Fig. 5.

Reduced prevalence of M. perstans infection following multiple rounds of IVM-MDA in Mamfe DHERF district but not in DHERF areas in the East. a, b Prevalence of M. perstans infection in community members residing in DHERF zones prior to MDA and after at least 8 or 10 years IVM therapy. In 2013, neither Lolodorf (n = 290) nor Batouri (n = 900) districts in eastern Cameroon had entered in MDA programmes. Messamena (n = 862) and Bertoua (n = 561) districts, also in the East, had received at least 8 rounds of MDA and the South West district of Mamfe had had > 10 rounds MDA (n = 1,276). Mamfe 0 refers to prevalence and intensity prior to MDA therapy (n = 640). c, d show mf counts in the different communities based on rounds of MDA (0, 8 > 10) or per district respectively. Statistical significance of the differences between groups indicated by the brackets were obtained after ANOVA/Kruskal-Wallis or Student's t-test/Mann-Whitney analysis depending on the normal distribution of the data