Table 2.

Univariable and multivariable associations with annual change in eGFR calculated by CKD-EPI equation

Variables	Univariate analysis		Multivariate analysisa
	Coefficient	P value	Coefficient	P value
Visfatin	−0.361	<0.001	−0.331	<0.001
Baseline GFR	−0.179	0.011	−0.234	0.001
Flow-mediated dilatation (FMD)	0.175	0.013	0.163	0.015
Systolic blood pressure	−0.162	0.022	−0.134	0.051
Fasting blood glucose	−0.149	0.035	−0.160	0.015
hsCRP level	−0.128	0.071	−0.060	0.365
LDL-cholesterol level	−0.103	0.143
Framingham risk score (%)	−0.093	0.191
Age	−0.090	0.204
Triglyceride level	−0.073	0.302
Uric acid level	−0.034	0.626
Body mass index	0.033	0.641

Abbreviations: eGFR, estimated glomerular filtration rate; CKD-EPI equation, Chronic Kidney Disease Epidemiology equation; hsCRP, high-sensitivity C-reactive protein; Framingham risk score included parameters with age, gender, total cholesterol, high-density lipoprotein, smoking, and systolic blood pressure; LDL, low-density lipoprotein.

^aThe multivariate regression model included all available variables with P value < 0.100 in the univariate analysis.