Table 2. Association between the novel complotype and AMD.
| Genotype combination for the novel complotype | N | P | OR | 95% CI |
||
|---|---|---|---|---|---|---|
| Contols | AMD | Lower | Upper | |||
| TT-GG-GG | 607 | 916 | 5.84*10−13 | – | – | – |
| TA-GG-GA | 47 | 23 | 1.01*10−5 | 0.3 | 0.174 | 0.51 |
| TA-GG-GG | 55 | 65 | 0.131 | 0.74 | 0.494 | 1.096 |
| TT-GA-GA | 74 | 47 | 6.65*10−7 | 0.36 | 0.237 | 0.535 |
| TT-GA-GG | 112 | 106 | 3.2*10−4 | 0.57 | 0.422 | 0.775 |
| TT-GG-AA | 59 | 48 | 0.007 | 0.56 | 0.373 | 0.856 |
| TT-GG-GA | 406 | 370 | 7.32*10−9 | 0.58 | 0.48 | 0.696 |
The model was established by logistic regression analysis, corrected for age and gender. Bonferroni corrected threshold for statistical significance is p < 0.008.