Table 3.

Association between baseline parameters and risk of ischemic stroke by univariable analyses^*

Parameter	Hazard ratio (95% CI)	P-value
Age	4.16 (2.13, 8.137)	<0.0001
Gender (M/F)	2.07 (0.74–5.74)	0.164
Previous niacin	0.56 (0.24–1.32)	0.186
On statin at baseline	0.75 (0.27–2.08)	0.578
Aspirin at baseline	0.51 (0.24–1.09)	0.085
Antiplatelet agents at baseline	0.75 (0.27–2.09)	0.582
ACE inhibitor/ARB	0.94 (0.50–1.77)	0.852
Any BP lowering drugs	0.69 (0.21–2.20)	0.526
History of Diabetes	0.92 (0.51–1.65)	0.768
History of PVD	1.02 (0.46, 2.27)	0.964
Previous MI	1.17 (0.67–2.062)	0.576
Previous Stroke/TIA	2.07 (1.17–3.67)	0.013
Hypertension	0.86 (0.47–1.58)	0.632
Atrial fibrillation	1.66 (0.74–3.70)	0.217
Metabolic syndrome	0.88 (0.44–1.76)	0.938
LDL cholesterol		0.740
Highest vs lowest tertile	0.76 (0.38–1.52)
Middle vs lowest tertile	0.87 (0.45–1.68)
Triglycerides		0.992
Highest vs lowest tertile	0.99 (0.50–1.97)
Middle vs lowest tertile	0.96 (0.49–1.88)
HDL cholesterol		0.349
Lowest vs highest tertile	1.52 (0.78–2.98)
Middle vs highest tertile	1.01 (0.48–2.13)
Total/HDL cholesterol ratio		0.909
Highest vs lowest tertile	0.86 (0.43–1.71)
Middle vs lowest tertile	0.94 (0.48–1.82)
ApoB		0.307
Highest vs lowest tertile	1.30 (0.67– 2.50)
Middle vs lowest tertile	0.74 (0.35 – 1.55)
ApoA		0.294
Highest vs lowest tertile	0.56 (0.28 – 1.16)
Middle vs lowest tertile	0.81 (0.42 – 1.56)
ApoB/ApoA ratio		0.234
Highest vs lowest tertile	1.31 (0.61 – 2.84)
Middle vs lowest tertile	1.82 (0.90 – 3.68)
LP(a)		0.044
Highest vs lowest tertile	2.27 (0.99 – 5.22)
Middle vs lowest tertile	2.78 (1.24 – 6.21)

^*Adjusted for age > 65 years (yes/no)