Table 1. Prevalence, 95% confidence intervals, and mean fluorescence intensity of IgG responses to each fragment of P. vivax DBP-RII, RBP1a-34 and RBP1b-32 in human patients and healthy individual serum samples.
| Antigen | No. of patient samples |
95% CIb | MFIc | No. of healthy samples |
95% CI | MFI | p valuee | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Positive | Negative | Total (%)a | Positive | Negative | Total (%)d | ||||||
| PvDBP-RII | 41 | 31 | 72 (56.9) | 45.4–67.7 | 5968.4 | 1 | 23 | 24 (95.8) | 79.8–99.3 | 2769.5 | p < 0.0001 |
| PvRBP1a-34 | 35 | 69 | 104 (33.7) | 25.3–43.2 | 5513.7 | 3 | 69 | 72 (95.8) | 88.5–98.6 | 3593.4 | p < 0.0001 |
| PvRBP1b-32 | 41 | 63 | 104 (39.4) | 30.6–49.0 | 5452.2 | 3 | 69 | 72 (95.8) | 88.5–98.6 | 2939.6 | p < 0.0001 |
aSensitivity: percentage of positive in patient samples.
bCI: confidence interval.
cMFI: mean fluorescence intensity.
dSpecificity: percentage of negative in healthy samples.
eDifferences in the total IgG prevalence for each antigen between vivax patients and healthy individuals were calculated with Student’s t-test. A p value of <0.05 is considered statistically significant.