Table 3. Comparison of perinatal outcomes by chorionicity and mode of conception.
| MCDA (n = 456) |
DCDA (n = 697) |
|||||||
|---|---|---|---|---|---|---|---|---|
| ART (n = 29) | SC (n = 427) | Unadjusted OR (95% CI) | Adjusted OR (95% CI)a | ART (n = 382) | SC (n = 315) | Unadjusted OR (95% CI) | Adjusted OR (95% CI)b | |
| Fetal loss–n (%) | 4 (13.8) | 46 (10.8) | 1.3 (0.4, 4.0) | 1.1 (0.3, 4.0) | 6 (1.5) | 2 (0.6) | 4.2 (0.5, 35.8) | 7.3 (0.8, 70.5) |
| Delivery < 28 wks–n (%) | 5 (17.2) | 58 (13.6) | 1.3 (0.5, 3.6) | 1.3 (0.3, 4.6) | 4 (1.0) | 3 (0.9) | 1.1 (0.2, 5.0) | 0.9 (0.2, 4.7) |
| Delivery < 32 wks–n (%) | 8 (27.6) | 94 (22.0) | 1.3 (0.6, 3.1) | 1.8 (0.7, 5.0) | 21 (5.3) | 22 (6.7) | 0.7 (0.4, 1.4) | 0.8 (0.4, 1.6) |
| BWD ≥ 25%–n (%) | 5 (21.7) | 61 (18.6) | 1.2 (0.4, 3.4) | 1.6 (0.4, 4.8) | 33 (8.5) | 25 (8.0) | 1.0 (0.5, 1.7) | 0.9 (0.5, 1.6) |
| Perinatal mortality–n (%)c | 2 (3.5) | 11 (1.3) | 2.7 (0.6, 12.6) | 2.5 (0.5, 12.6) | 4 (13.8) | 46 (10.8) | 1.7 (0.1, 18.2) | 2.6 (0.2, 32.9) |
| SGA–n (%)c | 10 (20.8) | 177 (26.0) | 0.8 (0.4, 1.5) | 0.9 (0.4, 2.0) | 5 (17.2) | 58 (13.6) | 1.0 (0.8, 1.3) | 1.1 (0.8, 1.4) |
| BW < 1500 gram–n (%)c | 7 (12.1) | 84 (9.8) | 1.3 (0.6, 2.9) | 1.7 (0.6, 4.5) | 8 (27.6) | 94 (22.0) | 1.3 (0.7, 2.3) | 1.4 (0.7, 2.5) |
| NICU admission–n (%)c | 28 (70.0) | 412 (68.0) | 1.1 (0.5, 2.2) | 1.5 (0.7, 3.4) | 5 (21.7) | 61 (18.6) | 1.0 (0.8, 1.3) | 1.0 (0.8, 1.3) |
aControlled for maternal age and body mass index.
bControlled for maternal age and parity.
cDenotes the single infants instead of twin pair.Multiple logistic regression test was used to calculate the odds ratio (OR). BW: birth weight; BWD: birth weight discordance; SGA: small for gestational age; NICU: neonatal intensive care center. ART: assisted reproductive technology; SC: spontaneous conception