Table 4. Comparison of maternal complications between MCDA and DCDA pregnancies by control of conception model.
| Spontaneously–conceived twin pregnancies (n = 742) |
ART–conceived twin pregnancies (n = 411) |
||||||
|---|---|---|---|---|---|---|---|
| MCDA (n = 427) | DCDA (n = 315) | Unadjusted OR (95% CI) | Adjusted OR (95% CI)a | MCDA (n = 29) | DCDA (n = 382) | OR (95% CI)b | |
| Gestational hypertension–n (%) | 11 (2.6) | 12 (3.8) | 1.5 (0.7, 3.4) | 1.9 (0.7, 5.1) | 2 (6.9) | 27 (7.1) | 1.0 (0.2, 4.5) |
| Preeclampsia–n (%) | 23 (5.4) | 31 (9.8) | 1.9 (1.1, 3.4) | 1.9 (1.0, 3.6) | 2 (6.9) | 40 (10.5) | 1.6 (0.4, 6.9) |
| GDM–n (%) | 42 (9.8) | 40 (12.7) | 1.3 (0.8, 2.1) | 1.1 (0.6, 1.8) | 3 (10.3) | 59 (15.45) | 1.6 (0.5, 5.4) |
| ICP–n (%) | 13 (3) | 6 (1.9) | 0.6 (0.2, 1.6) | 0.7 (0.2, 2.1) | 1 (3.5) | 27 (7.07) | 2.1 (0.3, 16.3) |
| Previa–n (%) | 10 (2.3) | 7 (2.2) | 0.9 (0.4, 2.5) | 1.5 (0.5, 4.2) | 3 (10.3) | 25 (6.54) | 0.6 (0.2, 2.1) |
| Placental abruption–n (%) | 0 (0) | 1 (0.3) | NA | NA | 0 (0) | 2 (0.52) | NA |
| PPH–n (%) | 37 (8.7) | 41 (13) | 1.6 (1.0, 2.5) | 1.8 (1.0, 3.0) | 6 (20.7) | 47 (12.3) | 0.5 (0.2, 1.4) |
| PPROM–n (%) | 63 (14.8) | 62 (19.7) | 1.4 (1.0, 2.1) | 1.5 (1.0, 2.5) | 8 (27.6) | 62 (16.23) | 1.0 (0.2, 4.5) |
| Maternal composite outcomes–n (%) | 166 (38.9) | 166 (52.7) | 1.8 (1.3, 2.4) | 1.7 (1.2, 2.4) | 18 (62.1) | 214 (56.02) | 1.6 (0.4, 6.9) |
NA: not applicable. GDM: gestational diabetes mellitus; ICP: intrahepatic cholestasis of pregnancies; PPH: Postpartum hemorrhage; PPROM: preterm previable rupture of membranes; ART: assisted reproductive technology.
aControlled for maternal age and body mass index. Multiple logistic regression test was used to calculate the odds ratio (OR).
bNo significant difference in maternal characteristics between the subgroup of MCDA and DCDA following ART. Univariate logistic regression test was used to calculate the OR.