Table 5. Comparison of perinatal outcomes between MCDA and DCDA pregnancies by control of conception model.
Spontaneously–conceived twin pregnancies (n = 742) |
ART–conceived twin pregnancies (n = 411) |
||||||
---|---|---|---|---|---|---|---|
MCDA (n = 427) | DCDA (n = 315) | Unadjusted OR (95% CI) | Adjusted OR (95% CI)a | MCDA (n = 29) | DCDA (n = 382) | OR (95% CI)b | |
Fetal loss–n (%) | 46 (10.8) | 1 (0.3) | 0 (0, 0.2) | 0.0 (0.0, 0.2) | 4 (13.8) | 5 (1.3) | 0.1 (0, 0.3) |
Delivery < 28 wks–n (%) | 58 (13.6) | 3 (1.0) | 0.1 (0, 0.2) | 0 (0, 0.2) | 5 (17.2) | 4 (1.1) | 0.1 (0, 0.2) |
Delivery < 32 wks–n (%) | 94 (22.0) | 20 (6.4) | 0.2 (0.1, 0.4) | 0.2 (0.1, 0.5) | 8 (27.6) | 18 (4.7) | 0.1 (0.1, 0.3) |
BWD ≥ 25%–n (%) | 61 (18.6) | 23 (7.7) | 0.4 (0.2, 0.6) | 0.4 (0.2, 0.7) | 5 (21.7) | 28 (7.5) | 0.3 (0.1, 0.8) |
Perinatal mortality–n (%)c | 11 (1.3) | 1 (0.2) | 0.1 (0, 0.9) | 0.1 (0, 0.9) | 2 (3.5) | 2 (0.3) | 0.1 (0, 0.5) |
SGA–n (%)c | 177 (26.0) | 115 (19.3) | 0.7 (0.5, 0.9) | 0.7 (0.5, 1.0) | 10 (20.8) | 143 (19.1) | 0.9 (0.4, 1.8) |
BW < 1500 g–n (%)c | 84 (9.8) | 20 (3.2) | 0.3 (0.2, 0.5) | 0.4 (0.2, 0.7) | 7 (12.1) | 31 (4.1) | 0.3 (0.1, 0.7) |
NICU admission–n (%)c | 412 (68.0) | 186 (32.8) | 0.2 (0.2, 0.3) | 0.2 (0.2, 0.3) | 12 (30) | 464 (67.4) | 0.2 (0.1, 0.4) |
BW: birth weight; BWD: birth weight discordance; SGA: small for gestational age; NICU: neonatal intensive care center. ART: assisted reproductive technology.
aControlled for maternal age and body mass index. Multiple logistic regression test was used to calculate the odds ratio (OR).
bNo significant difference in maternal characteristics between the subgroup of MCDA and DCDA following ART. Univariate logistic regression test was used to calculate the OR.
cDenotes the single infants instead of twin pair.