Table 6. Comparison of fetal outcomes by chorionicity and mode of conception: excluding TTTS, TAPS, TRAP and sIUGR of type II and III.
| ART (n = 404) |
SC (n = 574) |
|||||||
|---|---|---|---|---|---|---|---|---|
| MCDA (n = 22) | DCDA (n = 382) ref | Unadjusted OR (95% CI) | Adjusted OR (95% CI)a | MCDA (n = 259) | DCDA (n = 315) ref | Unadjusted OR (95% CI) | Adjusted OR (95% CI)b | |
| Fetal loss–n (%) | 0 (0) | 5 (1.3) | – | – | 7 (2.7) | 1 (0.3) | 8.7 (1.1, 71.3) | 8.7 (1.1, 71.2) |
| Delivery < 28 wks–n (%) | 3 (13.6) | 4 (1.1) | 14.9 (3.1, 71.5) | 14.4 (2.9, 71.0) | 11 (4.3) | 3 (1.0) | 4.6 (1.3, 16.7) | 7.7 (0.9, 63.0) |
| Delivery < 32 wks – n (%) | 5 (22.7) | 18 (4.7) | 5.9 (2.0, 17.9) | 5.3 (1.7, 16.4) | 23 (8.9) | 20 (6.4) | 1.4 (0.8, 2.7) | 1.3 (0.6, 2.8) |
| BWD ≥ 25%–n (%) | 3 (15.8) | 28 (7.5) | 2.3 (0.6, 8.4) | 2.3 (0.6, 8.6) | 16 (6.6) | 23 (7.7) | 0.9 (0.4, 1.6) | 0.8 (0.4, 1.9) |
| Perinatal mortality–n (%)c | 0 (0) | 2 (0.3) | – | – | 1 (0.2) | 1 (0.2) | 1.2 (0.1, 19.5) | 0.9 (0.1, 14.8) |
| SGA–n (%)c | 6 (15.8) | 143 (19.1) | 0.8 (0.3, 1.9) | 0.8 (0.3, 1.9) | 105 (21.6) | 115 (19.3) | 1.1 (0.9, 1.5) | 1.1 (0.8, 1.5) |
| BW < 1500 gram–n (%)c | 4 (9.1) | 31 (4.1) | 2.4 (0.8, 7.0) | 2.0 (0.7, 6.2) | 21 (4.1) | 20 (3.2) | 1.3 (0.7, 2.4) | 0.9 (0.4, 2.1) |
| NICU admission–n (%)c | 24 (72.7) | 224 (32.6) | 5.5 (2.5, 12.1) | 5.2 (2.4, 11.5) | 294 (63.4) | 186 (32.8) | 3.5 (2.7, 4.6) | 3.3 (2.4, 4.4) |
Multiple logistic regression test was used to calculate the odds ratio (OR). ART: assisted reproductive technology; SC: spontaneous conception.
aControlled for maternal pre-existing diseases.
bControlled for maternal BMI and age.
cDenotes the single infants instead of twin pair.