Figure 5.

Effect of intra-basolateral division of the amygdala (BL-d) recombinant adeno-associated viral vector (rAAV)-mediated Ghrelin receptor (Ghr-R) overexpression on behavior in the open field test during basal conditions and after 15-minute restraint stress (n=8–12). (a-c) Ghr-R overexpression caused significantly increased center entries and a trend towards increased center time and distance moved in the open field. (d-f) After 15 minutes of restraint stress, the mice had decreased center entries, spent decreased time in the center, and moved a shorter distance, but there was no difference between Ghr-R-overexpressing and empty vector control mice on either parameter tested. Asterisk indicates statistical significance in unpaired Student’s t test (*P<.05).