FIG 5.

Correlation between the numbers of IUPM obtained by the Mϕ-QVOAs and numbers of SIV RNA copies in tissue. (A to C) Correlation between the numbers of IUPM from brain Mϕ-QVOA and numbers of SIV RNA copies in basal ganglion tissue (A) and parietal cortex tissue (B) and the CSF viral load (C); (D) correlation between the numbers of IUPM in lung macrophages and the numbers of IUPM in BAL fluid macrophages. Each symbol represents a single animal, and symbols in red represent animals with severe CNS disease. Significance was determined by Spearman's rank correlation; a P value of <0.05 was considered significant.