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. 2016 May 27;90(12):5541–5548. doi: 10.1128/JVI.00192-16

TABLE 2.

Frequencies of m3KOΔnef mutations detectable in virus populations at necropsya

nt position of original mutation Frequency (%) in animal:
cy0381 cy0348 cy0382
1316 99.8 95.7 96.6
1481 64.4 <5 47.6
1510 99.7 <5 48.3
2467 99.7 99.6 99.4
2723 99.6 84.1 99.8
2850 99.8 95.5 99.7
2860 99.9 96.6 99.5
3721 99.9 99.7 99.9
4260 99.8 92.6 99.8
4945 99.5 99.5 99.4
5815 100.2 99.9 99.8
6199 98.9 97.0 96.5
6639 99.4 65.6 99.7
6923 97.4 11.6 98.1
6925 97.4 11.6 98.1
7058 99.8 99.8 99.8
8390 98.0 11.3 97.7
8750 56.4 6.8 87.4
8850 92.1 52.3 25.5
9110 99.7 99.7 99.5
9176 85.0 5.2 5.3
9181 84.0 46.7 6.0
a

The nucleotide (nt) positions in the m3KOΔnef inoculum virus that had the original mutations, relative to SIVmac239, are shown. The frequencies of the individual variants, relative to SIVmac239, are shown for each of the virus populations isolated from the three animals. This percentage reflects the frequency that the original mutation from the m3KOΔnef inoculum was still found in the virus population at necropsy.