TABLE 2.
nt position of original mutation | Frequency (%) in animal: |
||
---|---|---|---|
cy0381 | cy0348 | cy0382 | |
1316 | 99.8 | 95.7 | 96.6 |
1481 | 64.4 | <5 | 47.6 |
1510 | 99.7 | <5 | 48.3 |
2467 | 99.7 | 99.6 | 99.4 |
2723 | 99.6 | 84.1 | 99.8 |
2850 | 99.8 | 95.5 | 99.7 |
2860 | 99.9 | 96.6 | 99.5 |
3721 | 99.9 | 99.7 | 99.9 |
4260 | 99.8 | 92.6 | 99.8 |
4945 | 99.5 | 99.5 | 99.4 |
5815 | 100.2 | 99.9 | 99.8 |
6199 | 98.9 | 97.0 | 96.5 |
6639 | 99.4 | 65.6 | 99.7 |
6923 | 97.4 | 11.6 | 98.1 |
6925 | 97.4 | 11.6 | 98.1 |
7058 | 99.8 | 99.8 | 99.8 |
8390 | 98.0 | 11.3 | 97.7 |
8750 | 56.4 | 6.8 | 87.4 |
8850 | 92.1 | 52.3 | 25.5 |
9110 | 99.7 | 99.7 | 99.5 |
9176 | 85.0 | 5.2 | 5.3 |
9181 | 84.0 | 46.7 | 6.0 |
The nucleotide (nt) positions in the m3KOΔnef inoculum virus that had the original mutations, relative to SIVmac239, are shown. The frequencies of the individual variants, relative to SIVmac239, are shown for each of the virus populations isolated from the three animals. This percentage reflects the frequency that the original mutation from the m3KOΔnef inoculum was still found in the virus population at necropsy.