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. Author manuscript; available in PMC: 2016 May 31.
Published in final edited form as: Ageing Res Rev. 2015 Jan 3;23(Pt A):3–11. doi: 10.1016/j.arr.2014.12.009

Table 1. Overview of DNA repair pathways.

Repair system Type of lesions Accuracy
Base Excision Repair (BER) Oxidative lesions error free
Nucleotide Excision Repair (NER) Helix-distorting lesions error free
Translesion synthesis Various lesions error prone
Miss Match Repair (MMR) Replication errors error free
Single Stand Break Repair (SSBR) Single strand breaks error free
Homologous Recombination (HR) Double-strand breaks mostly error free
Non-Homologous End Joining (NHEJ) Double-strand breaks mostly error prone
DNA Interstrand Crosslink Repair Pathway Interstrand crosslinks largely error free