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. Author manuscript; available in PMC: 2016 May 31.
Published in final edited form as: Chem Zvesti. 2014 Nov 28;69(1):90–111. doi: 10.1515/chempap-2015-0052

Figure 2.

Figure 2

Synthesis of N-glycans. In the initial stage a glycan precursor Glc3Man9ClcNAc2 is formed attached to the membrane and then transferred to the protein backbone. In the next step two Glc and one Man units are trimmed and the glycan attached to the protein backbone is then further processed in the Golgi apparatus. If the glycan has a correct composition it is secreted away from the Golgi apparatus for proper functioning inside the cell. When glycan has an incorrect composition it is transferred to lysosome to be recycled. Adapted from (Nakayama et al., 2013).