Table 2.
Pathologic features of kidney biopsy at presentation
| C3 dominant | C3 co-dominant | |
|---|---|---|
| LM | ||
| Exudative GN | 11 (85%) | 10 (100%) |
| Mesangial hypercellularity | 7 (54%) | 7 (70%) |
| Crescents | 7 (54%) | 3 (30%) |
| <50% | 4 (31%) | 3 (30%) |
| >50% | 3 (23%) | 0 |
| Global glomerulosclerosis | ||
| None | 9 (69%) | 8 (80%) |
| <50% | 3 (23%) | 2 (20%) |
| >50% | 1 (8%) | 0 |
| IF/TA | ||
| None | 9 (69%) | 8 (80%) |
| Mild | 3 (23%) | 2 (20%) |
| Moderate | 1 (8%) | 0 |
| Severe | 0 | 0 |
| IF | ||
| Starry-sky | 12 (92%) | 5 (50%) |
| Garland | 1 (8%) | 5 (50%) |
| EM | ||
| Subepithelial ‘humps’ | 13 (100%) | 10 (100%) |
| Intramembranous deposits | 13 (100%) | 6 (60%) |
LM, light microscopy; GN, glomerulonephritis; IF/TA, interstitial fibrosis and tubular atrophy; IF, immunofluorescence; EM, electron microscopy.