Figure 1.

Kaplan–Meier plots of kidney survival among 168 patients with primary hyperoxaluria (PH) who did not have end-stage renal disease (ESRD) at diagnosis. Patients are shown by quartile of urine oxalate excretion (normal <0.45 mmol/1.73 m²/day). Patients in the highest quartile of urine oxalate excretion of ≥2.4 had the worst renal survival (42% at 20 years following diagnosis), compared with renal survival of 95% 20 years following diagnosis in those who had <1.6 mmol/1.73 m²/day. Reprinted from ref. 12.