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. 2016 May 31;11(5):e0156169. doi: 10.1371/journal.pone.0156169

Table 4. Results of Multiple Mediation Analyses for the MDD Group.

MDD, Major Depressive Disorder; BC 95% CI, bias-corrected 95% confidence interval.

Mediation Pathway Point Estimate SE BC 95% CI
Lower Upper
Neuroticism → Cognitive variables → Anxiety symptoms
Indirect effects
TOTAL 1.61 0.52 0.71 2.81
Worry 1.25 0.41 0.46 2.10
Brooding 0.37 0.27 -0.08 1.03
Reflection -0.01 0.07 -0.19 0.14
Contrasts
Worry vs. brooding 0.88 0.49 -0.08 1.87
Worry vs. reflection 1.25 0.41 0.46 2.10
Brooding vs. reflection 0.37 0.27 -0.09 1.00
Neuroticism → Cognitive variables → Depressive symptoms
Indirect effects
TOTAL 1.61 0.60 0.59 3.04
Worry -0.01 0.13 -0.45 0.14
Brooding 1.63 0.53 0.77 2.96
Reflection -0.01 0.15 -0.37 0.28
Contrasts
Worry vs. brooding -1.65 0.54 -2.97 -0.77
Worry vs. reflection -0.01 0.19 -0.44 0.36
Brooding vs. reflection 1.64 0.53 0.77 2.96