Fig 1. Comparison of the impact of Lactobacillus casei strains on the composition of cecal microbiome.
Mice were administered 1 dose (108 CFU/mouse/day) daily of L. casei 12A, ATCC334, 32G, CRF28, UW1, BL23 or M36 for 1 week and sacrificed 3.5h after the last dose. (A) Pair wise comparison of the OTUs at genus level detected in the cecal microbiome of each treatment. A Monte-Carlo test with 10,000 replicates was utilized to identify treatments that were significantly (p≤0.05) different. The values with p≤0.05 are highlighted. (B) Predominant genera in the cecum microbiome of mice administered L. casei strains. Treatments that are not significantly (p≤0.05) different are clustered together. Only genera that comprise greater than 5% of the total microbiome in at least one treatment are presented (n: 6 for each bar).