Table 1. Bacterial genera detecteda in cecum content of mice administered saline (control) or Lactobacillus casei strainsb.
Taxon | Percentage (mean ± SE)cd | |||||||
---|---|---|---|---|---|---|---|---|
Control | 12A | ATCC334 | 32G | CRF28 | UW1 | BL23 | M36 | |
Bacteroidales S24-7 IS | 31.8±8.6 | 37.0±14.7 | 35.2±7.3 | 29.3±4.9 | 36.3±9.2 | 20.4±6.2 | 19.8±10.0 | 37.6±9.5 |
Lachnospiraceae IS | 30.4±9.4 | 24.5±6.4 | 24.2±7.4 | 28.3±10.3 | 20.7±5.8 | 42.3±10.9 | 45.5±11.0 | 18.6±6.3 |
Oscillospira | 15.5±10.8 | 16.8±5.2 | 18.7±5.4 | 28.5±11.8 | 30.0±7.6 | 14.8±4.0 | 15.2±5.1 | 24.1±5.3 |
Ruminococcaceae;Other | 9.6±4.1 | 11.7±3.3 | 13.0±6.2 | 5.5±2.2 | 5.2±1.3 | 8.4±1.6 | 8.2±1.7 | 8.8±2.6 |
Allobaculum | 2.7±6.4 | BQL | BQL | 0.2±0.4 | BQL | 0.0±0.0 | BQL | 0.0±0.1 |
Clostridiales;Other;Other | 2.0±0.6 | 1.8±0.4 | 1.0±0.0 | 2.0±0.6 | 1.7±0.5 | 2.0±0.8 | 2.2±0.8 | 1.2±0.7 |
Anaeroplasma | 1.8±1.8 | 1.3±0.5 | 1.3±0.5 | 1.0±1.5 | 1.5±1.0 | 0.6±0.5 | 0.3±0.5 | 1.2±1.4 |
Lachnospiraceae;Other | 1.7±0.5 | 2.2±0.8 | 2.3±1.5 | 0.8±0.4 | 0.7±0.5 | 1.5±0.3 | 1.5±0.5 | 1.5±0.8 |
Clostridia;Other | 1.3±1.1 | 1.0±0.6 | 1.0±0.6 | BQL | 0.2±0.4 | 0.4±0.1 | 0.3±0.5 | 0.4±0.2 |
Ruminococcus | 0.9±0.4 | 1.2±0.4 | 1.3±0.5 | 1.0±0.0 | 1.0±0.0 | 0.7±0.2 | 0.7±0.5 | 0.9±0.1 |
Firmicutes;Other | 0.6±0.2 | 0.7±0.8 | 0.8±0.4 | 1.3±1.5 | 0.8±0.4 | 7.5±6.7 | 5.8±5.7 | 2.4±2.7 |
Bacteria;Other | 0.4±0.1 | 0.2±0.4 | BQL | 1.2±0.4 | 1.2±0.4 | 1.0±0.2 | 0.2±0.4 | 0.9±0.2 |
Ruminococcaceae IS | 0.3±0.1 | BQL | 0.3±0.5 | 0.3±0.5 | BQL | 0.2±0.1 | BQL | 0.3±0.1 |
Akkermansia | 0.1±0.2 | BQL | BQL | BQL | BQL | BQL | BQL | BQL |
Lactobacillus | 0.0±0.0 | BQL | BQL | BQL | BQL | BQL | BQL | 1.8±4.3 |
Number of alterationse | - | - | 2 | 4 | 6 | 7 | 5 | 6 |
aOnly genera that were present at ≥1% in a sample are included in this table.
bMice were administered 1 dose (108 CFU/mouse/day) daily of L. casei strains for 1 week and sacrificed 3.5h after the last dose.
cThe detection limit was 0.00009 and this value was used to calculate the p-value.
dGenera that differ from control within each group are shown in bold (p≤0.05). The statistical difference was examined using the Monte-Carlo test.
eThe number of genera that differed from the control for that treatment.
IS: Incertae Sedis.
BQL: Below quantifiable limit.