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. 2016 May 31;11(5):e0156376. doi: 10.1371/journal.pone.0156376

Table 3. 45 studies examined the ZIKV characteristics: genotype, molecular characterisation, pathogenic attributes and virus propagation in mice.

Number of studies
Genotype reported:
Asian lineage 33
East/Central/South African lineage (Uganda) 9
West African lineage (Senegal/Nigerian) 5
Molecular characterisation:
Phylogeny was reported (e.g. dentogram, tree) 26
Virus was reported to be partially or fully sequenced 25
Evolution of the virus discussed 12
Examined proportion of nucleotide identities among strains and/or codon adaptation and fitness 5
Pathogenic attributes:
Virus propagation in mice via intracerebral inoculation 4
Antigenic relatedness of Flaviviruses 2
Viral entry into cells 2
Virus morphology (ZIKV: 40 mµ, spherical in shape) 1
Presence of virus-specific antigen in the nuclei of Zika virus-infected cells (vertebrate & invertebrate) 1
Virus growth in vitro 1
Virus spread within mice 1
Virus propagation in chick embryos 1