Table 2.
Participants’ clinical characteristics in three age groups
| Subjects <45 years
|
Subjects 45–60 years
|
Subjects >60 years
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Females (n=23) | Males (n=50) | F vs M
|
Females (n=59) | Males (n=55) | F vs M
|
Females (n=52) | Males (n=40) | F vs M
|
|
| P-value | P-value | P-value | |||||||
| Age (years) | 38.9±4.8 | 36.9±5.5 | 0.194 | 54.4±3.4 | 53.3±4.1 | 0.144 | 64.7±4.3 | 65.0±5.0 | 0.752 |
| BMI (kg/m2) | 26.9±4.5 | 29.1±3.8 | 0.059 | 28.6±5.2 | 29.2±4.1 | 0.506 | 28.6±4.6 | 28.6±3.8 | 0.999 |
| Waist circumference (cm) | 87±13 | 100±12 | 0.002 | 89±12 | 105±10 | <0.001 | 91±12 | 103±12 | <0.001 |
| Hip circumference (cm) | 105±8 | 111±9 | 0.049 | 105±11 | 108±6 | 0.321 | 110±9 | 106±9 | 0.185 |
| WHR | 0.83±0.08 | 0.91±0.07 | 0.003 | 0.84±0.07 | 0.97±0.06 | <0.001 | 0.83±0.08 | 0.97±0.05 | <0.001 |
| Number (percentage) of patients with hypertension | 7 (30.4) | 14 (51.8) | 0.214 | 33 (55.9) | 35 (63.6) | 0.448 | 38 (73.1) | 33 (82.5) | 0.289 |
| SBP (mmHg) | 122±14 | 132±14 | 0.020 | 133±17 | 136±15 | 0.433 | 138±22 | 136±17 | 0.575 |
| DBP (mmHg) | 81±12 | 75±10 | 0.045 | 78±10 | 77±10 | 0.558 | 75±11 | 74±11 | 0.649 |
| MAP (mmHg) | 95±12 | 94±11 | 0.734 | 96±11 | 96±11 | 0.974 | 96±13 | 94±11 | 0.573 |
| PP (mmHg) | 41±8 | 57±8 | <0.001 | 56±13 | 59±11 | 0.124 | 64±16 | 62±15 | 0.694 |
| HR (/min) | 75±10 | 72±9 | 0.393 | 73±10 | 69±8 | 0.010 | 68±10 | 68±10 | 0.959 |
| Number (percentage) of patients with type 2 diabetes | 2 (8.7) | 5 (18.5) | 0.416 | 20 (33.9) | 29 (52.7) | 0.259 | 18 (34.6) | 16 (40.0) | 0.665 |
| Glucose levela (mg/dL) | 92±9 | 94±12 | 0.591 | 103±32 | 107±18 | 0.625 | 102±12 | 107±37 | 0.528 |
| Number (percentage) of patients with dyslipidemia | 11 (47.8) | 22 (81.5) | 0.842 | 44 (74.6) | 42 (76.4) | 0.536 | 48 (92.3) | 28 (70.0) | 0.011 |
| Number (percentage) of patients with treated dyslipidemia | 0 (0.0) | 6 (22.2) | 0.025 | 3 (5.1) | 4 (7.3) | 0.710 | 13 (25.0) | 5 (12.5) | 0.186 |
| TC levela (mg/dL) | 214±36 | 220±42 | 0.631 | 225±41 | 212±39 | 0.076 | 231±48 | 210±32 | 0.025 |
| LDL cholesterol levela (mg/dL) | 120±34 | 137±38 | 0.130 | 131±38 | 128±37 | 0.718 | 135±51 | 126±27 | 0.350 |
| HDL cholesterol levela (mg/dL) | 64±24 | 48±15 | 0.007 | 54±15 | 48±9 | 0.016 | 62±16 | 52±12 | 0.003 |
| TG levela (mg/dL) | 149±112 | 161±72 | 0.654 | 151±77 | 165±126 | 0.528 | 149±60 | 148±117 | 0.953 |
| Number (percentage) of smokers | 11 (47.8) | 15 (55.6) | 0.794 | 23 (39.0) | 21 (38.2) | 0.917 | 11 (21.2) | 13 (32.5) | 0.323 |
| CRP level (mg/L) | 3.30±5.74 | 1.36±1.17 | 0.362 | 1.58±1.43 | 3.57±6.96 | 0.260 | 3.11±2.41 | 2.60±2.26 | 0.546 |
| Number (percentage) of patients with metabolic syndrome | 8 (34.8) | 14 (51.8) | 0.354 | 27 (45.8) | 24 (43.6) | 0.968 | 31 (59.6) | 19 (47.5) | 0.344 |
| LV ejection fraction % | 70.4±4.9 | 65.0±7.3 | 0.010 | 70.1±6.0 | 69.6±6.8 | 0.695 | 69.6±8.5 | 70.2±7.4 | 0.758 |
Notes:
a
Morning fasting serum concentration. Data presented as mean ± SD or n (%) parameter values. Data in bold indicates statistical significance.
Abbreviations: F, females; M, males; BMI, body mass index; WHR, waist-to-hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; PP, pulse pressure; HR, heart rate; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides; CRP, C-reactive protein; LV, left ventricle.