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. 2016 May 24;11:2251–2264. doi: 10.2147/IJN.S102268

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© 2016 Ren et al. This work is published and licensed by Dove Medical Press Limited

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The effects of SiNPs on the quality and quantity of sperms in epididymides.

Notes: (A–C) SiNPs decreased the sperm concentration and the sperm motility, and increased the sperm abnormity on the 45th day after the first dose. (D–F) The sperm concentration, the sperm motility, and the sperm abnormity in the SiNPs group had no significant difference compared with the saline control group on the 75th day after the first dose. Data are expressed as the mean ± standard error from three independent experiments. *P<0.05 vs the saline control group. Saline group represents the saline control group. The data indicated that SiNPs could decrease the quality and quantity of sperms.

Abbreviation: SiNPs, silica nanoparticles.