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. Author manuscript; available in PMC: 2016 May 31.
Published in final edited form as: Nano Lett. 2016 Jan 19;16(2):1194–1200. doi: 10.1021/acs.nanolett.5b04495

Figure 1.

Figure 1

(A) Schematic displaying the surface modifications for the immobilization of glucose oxidase to the nanopipette tip. First, the inner surface of quartz nanopipette is coated with PLL. Then the surface is treated with gluteraldehyde to cross-link the amino group of PLL and that of glucose oxidase. (B) Electrochemical characterization of nanopipette after each modification step. Supporting electrolyte was 10 mM PBS (pH 7.0). (C) Typical SEM image of the nanopipette tip. Inset displays the tip geometry. (D) Enzymatic conversion of D-glucose to hydrogen peroxide and gluconic acid.