Table 2.
Dementia | AD | VaD | ||||
---|---|---|---|---|---|---|
| ||||||
RR | 95% CI | RR | 95% CI | RR | 95% CI | |
|
||||||
All | 1.42 | 0.93, 2.18 | 1.80 | 1.00, 3.29* | 1.73 | 0.47, 6.31 |
(n=4) | (n=4) | (n=3) | ||||
Baseline age (y) | ||||||
<60 | 1.74 | 1.34, 2.26* | 3.10 | 2.19, 4.38*,† | 5.01 | 2.97, 8.43*,† |
60+ | 1.31 | 0.71, 2.39 | 1.38 | 0.94, 1.66* | 0.90 | 0.49, 1.64 |
(n= 1 and 3) | (n= 1 and 3) | (n= 1 and 2) | ||||
Sex | ||||||
Men | 1.59 | 1.17, 2.15* | 2.32 | 1.37, 3.92* | 4.07 | 1.93, 8.58* |
Women | 2.07 | 1.49, 2.88* | 3.00 | 2.09, 4.33* | 3.70) | 1.99, 6.88* |
(n=3 and 1) | (n=2 and 2) | (n= 2 and 2 | ||||
Follow-up time (y) | ||||||
<10 | 1.17 | 0.54, 2.54 | 1.32 | 0.87, 1.99† | 0.90 | 0.49, 1.64† |
≥10 | 1.75 | 1.36, 2.25* | 2.91 | 2.10, 4.03* | 5.01 | 2.98, 8.43* |
(n=2 and 2) | (n=2 and 2) | (n=2 and 1) |
P<0.05 for the null hypothesis that lnRR=0.
Significant test for heterogeneity (Q-test) with 1 degrees of freedom, comparing RRs between sex, baseline age and follow-up strata: P-value<0.05.
Models were adjusted for socio-demographic factors in addition to some lifestyle factors, co-morbid conditions and/or genetic factors (mainly ApoE ε4 carrier status).
AD: Alzheimer’s Disease; VaD: Vascular Dementia; RR: Relative Risk; n: study datapoint used in fully adjusted models.