The PAX3 promoter contains two highly conserved FOXD3 sites, F1 and F2. (A) Schematic of the PAX3 promoter, with the locations of the ATG, CDS start, and conserved elements NCE1 and NCE2. Two putative FOXD3 sites, F1 and F2, are indicated. (B) Sequence of the NCE1 and NCE2 enhancer islands within the PAX3 promoter. The sequence numbering is in relation to the translational start site, which is numbered +1. The dotted boxes indicate the NCE1 and NCE2 islands of sequence homology between human and mouse sequences. Putative FOX long sites are shown by black boxes.