. Author manuscript; available in PMC: 2017 Jun 1.

Published in final edited form as: Ann Neurol. 2016 Apr 18;79(6):907–920. doi: 10.1002/ana.24641

Table 1.

Pearson correlation analysis of the MRI metrics versus IHC quantifications (n=75).

r	Corpus Callosum					Cortex
r	SMI31	MBP	GFAP	Iba1	DAPI	NeuN	GFAP	Iba1	DAPI
FA	0.66^**	0.13	−0.18	−0.36^*	−0.25	−0.04	0.63^**	−0.06	−0.13
AD	0.65^**	−0.01	−0.26	−0.23	−0.66^**	0.03	0.20	0.26	0.51^**
RD	−0.39^**	−0.46^**	0.28	0.50^**	0.31^*	0.05	0.31^*	0.24	0.49^**
MD	0.24	−0.17	0.02	−0.30^*	−0.25	0.34^*	0.29^*	0.24	0.59^**
MTR-3.5	0.51^**	0.38^**	−0.07	−0.25	0.07	0.221	−0.16	0.02	−0.06
MTR-20	0.23	0.28	0.64^**	0.05	−0.16	−0.09	0.42^**	−0.12	−0.19

p < 0.01,

^**

p < 0.05.

AD = axial diffusivity; DAPI = 4,6-diamidino-2-phenylindole; FA = fractional anisotropy; GFAP = glial fibrillary acidic protein; Iba1 = ionized calcium-binding adaptor molecule 1; MBP = myelin basic protein; MD = mean diffusivity; MTR = magnetization transfer ratio; NeuN = hexaribonucleotide binding protein 3; RD = radial diffusivity; SMI31 = phosphorylated neurofilament H.