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This work reviews the general theory of: (1) thermodynamics, energies, mobility, and production of defects; (2) theory of annealing; (3) analysis of annealing curves; (4) influence of point defects on physical properties; (5) experimental investigations of the effects of quenching, irradiation, annealing and diffusion. The energy of formation EF of (monovacancy) defects is given as 1.09 eV. The change in electrical resistivity per electron flux (number of incident particles per cm2) is plotted as a function of energy of incident electrons, and then replotted as the displacement cross section for moving a silver atom from a lattice site by incident electrons, again as a function of energy of incident electrons. The threshold energy ED for displacing a silver atom from its lattice site is given as 28 eV, and the resistivity change per unit of defect concentration in “atomic percent” (mole fraction) △ρF is 1.4 μΩ·cm/(at/o). The damage rate under fast-neutron irradiation at 20 °C at a flux of 7×1011 cm2·s−1 is 3.35×10−11 Ω·cm/h. The neutron exposure required to produce 1at/° of vacancy-interstitial pairs is 1.05×1020 nvt of fast neutrons (n is number density of neutrons, v is velocity, t is time; nvt is neutron fluence, number per second per unit area).