Table 1. Baseline characteristics of VAE patients.
Characteristic | VAE-VAC (n = 142) | VAE-IVAC+ (n = 46) | P value |
---|---|---|---|
Age, y | 59.1 ± 17.6 | 62.7 ± 15.1 | .21 |
Sex, % male | 69.7 (99) | 69.5 (32) | >.99 |
BMI | 30.4 ± 10.1 | 30.5 ± 7.7 | .91 |
Medical history | |||
Coronary artery disease | 29.6 (42) | 28.3 (13) | >.99 |
Neoplastic disease | 23.3 (33) | 21.7 (10) | >.99 |
Solid organ transplant | 0.70 (1) | 4.36 (2) | .14 |
Antibiotics in preceding 90 d | 52.8 (75) | 41.3 (19) | .23 |
Corticosteroids in preceding 90 d | 19.7 (28) | 26.1 (12) | .41 |
APACHE III score | 82.0 ± 27.5 | 81.9 ± 25.0 | .98 |
SOFA score day 1 | 8.6 ± 4.1 | 8.3 ±3.9 | .66 |
Hospital length of stay, d | 38.4 ± 28.5 | 36.6 ± 27.5 | .70 |
ICU length of stay, d | 20.0 ± 18.5 | 17.1 ± 14.9 | .29 |
Invasive ventilation duration stay, d | 15.4 (12.5) | 12.6 (9.4) | .11 |
Tracheostomy present? | 0.7 (1) | 2.1 (1) | .43 |
Admitting ICU | |||
Coronary care | 1.1 (2) | 0 (0) | |
Cardiovascular surgery | 17.6 (33) | 7.98 (15) | |
Medical ICU | 17.1 (32) | 0.5 (8) | |
Surgical ICU | 21.3 (40) | 8.0 (15) | |
Medical-surgical ICU | 6.38 (12) | 2.6 (5) | |
Neurologic ICU | 6.91 (13) | 1.1 (2) | |
Respiratory care or step-down unit | 5.32 (10) | 0.5 (1) |
NOTE. Values are mean ± SD, % (n), or as otherwise indicated.
APACHE III, Acute Physiology and Chronic Health Evaluation Score III; BMI, body mass index; ICU, intensive care unit; IVAC+, Infectious ventilator associated complications and ventilator associated pneumonia; SOFA, sequential organ failure assessment; VAC, ventilator-associated complication; VAE, ventilator-associated event.