. Author manuscript; available in PMC: 2017 Jun 1.

Published in final edited form as: Curr Opin Cell Biol. 2016 Mar 22;40:81–89. doi: 10.1016/j.ceb.2016.03.002

Table 1.

Ubiquitin ligases implicated in nuclear PQC degradation

Ubiquitin ligase	Species studied	Localization	Key references
San1	Yeast	Nucleus	[10,12,30]
Ubr1	Yeast/mammals	Cytoplasm/nucleus?	[16,17,37]
Doa10/Ssm4	Yeast	ER membrane/inner nuclear membrane	[19,20,45]
Asi complex (Asi1, 2, 3)	Yeast	Inner nuclear membrane	[50,51]
Slx5-Slx8	Yeast	Nucleus	[52,53]
PML-IV/RNF4	Mammals	Nucleus	[54–58]
UHRF-1	Mammals	Nucleus	[59]
UHRF-2	Mammals	Nucleus	[59]