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. 2016 May 17;24(6):374–389. doi: 10.1007/s12471-016-0845-3

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© The Author(s) 2016

Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Methodological quality of the included studies. Methodological quality of the included studies was assessed on the following domains of potential bias: completeness of data (selection bias), standardisation of prognostic factors and study outcome (information bias) and statistical calculation of effect size (study outcome)