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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Pharmacol Ther. 2016 Apr 25;163:48–57. doi: 10.1016/j.pharmthera.2016.03.016

Table 4.

MicroRNA biomarker candidates for drug-induced kidney injury (DIKI)

microRNARNA DIKI (Model) Species Biofluid Direction Reference
let-7g, miR-93, -191, -195 Cisplatin Rat Urine UP (Kanki, et al., 2014)
miR-15, -16, -20a, -192, -193, -210 Cisplatin Rat Urine UP (Pavkovic, et al., 2014)
miR-21, -200c, -423 Cisplatin, Acetaminophen Patients Urine UP (Pavkovic, Robinson- Cohen, et al., 2015)
miR-203a, let-7d Gentamicin Rat Urine DOWN (Nassirpour, et al., 2014)
miR-21, miR-155 Gentamicin Rat Urine DOWN (Saikumar, et al., 2012)
miR-30a,c,e Contrast agent* Rat Patients Plasma UP (Gutierrez-Escolano, et al., 2015)
miR-320 Gentamicin Rat Urine UP (Nassirpour, et al., 2014)
miR-34c Doxorubicin Rat Urine UP (Church, et al., 2014)
*

iohexhol + furosemide + indomethacin were used for rats