Skip to main content
. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Diabetes Res Clin Pract. 2016 Jan 15;115:115–121. doi: 10.1016/j.diabres.2016.01.021

Table 1. Baseline characteristics of REGARDS participants with diabetes by the use of Calcium Chanel Blockers (CCB), n = 4978.

Characteristics Non-users, n = 3494 CCB users, n = 1484 Verapamil users, n = 174


n (%) n (%) P n (%) P
Socio-demographics
 Age, mean years, SD 64.9 ± 8.8 66.2 ± 8.5 <0.001 66.1 ± 8.7 0.09
 African American 1795 (51.4) 1007 (67.9) <0.001 121 (69.5) <0.001
 Female 1771 (50.7) 840 (56.6) <0.001 109 (62.6) 0.002
 Geographical region 0.70 0.45
  Stroke belt 1256 (35.9) 515 (34.7) 70 (40.2)
  Stroke buckle 811 (23.2) 352 (23.7) 35 (20.1)
  Non-belt 1427 (40.8) 617 (41.6) 69 (39.7)
 Did not graduate from high school 605 (17.3) 324 (21.9) <0.001 40 (23.0) 0.001
 Income < $35,000 1743 (49.9) 830 (55.9) <0.001 108 (62.1) 0.06
Behaviors
 Current smoking 490 (14.1) 198 (13.4) 0.83 22 (12.6) 0.62
 Any alcohol use 909 (26.8) 344(23.6) 0.03 41(24.0) 0.37
 Not physically active 1354 (39.3) 645 (44.2) <0.001 74 (43.3) 0.30
 Medication non-adherence 1034 (31.0) 459 (31.7) 0.66 56 (32.7) 0.67
Other medical conditions
 CHD 868 (24.8) 439 (29.6) <0.001 42 (24.1) 0.83
 Other CVD 418 (12.0) 233 (15.7) <0.001 16 (9.2) 0.27
 Hypertension 2466 (70.7) 1409 (95.0) <0.001 168 (96.6) <0.001
Physiological
 Waist circumference, cm, mean, SD 104.5 ± 15.4 105.8 ± 15.9 <0.001 106.6 ± 15.7 0.08
 Systolic blood pressure, mmHg, mean, SD 130.7 ± 16.9 134.3 ± 17.3 <0.001 139.3 ± 18.2 <0.001
 Total cholesterol mg/dL, mean, SD 183.2 ± 42.6 178.1 ± 40.8 <0.001 182.8 ± 43.6 0.91
 HDL-C, mg/dl, mean, SD 46.3 ± 14.0 48.0 ± 14.3 <0.001 49.5 ± 16.0 0.004
 Albumin to creatinine ratio, median, IQR 11.0 [5.8–30.4] 16.7 [7.5–70.8] <0.001 17.9 [6.6–70.8] <0.001
 Heart Rate, beat/min, mean, SD 71.1 ± 33.8 69.6 ± 12.4 0.02 69.4 ± 11.2 0.10
Diabetes management
 Any anti-diabetic medication or insulin use 2569 (73.5) 1188 (80.1) <0.001 145 (83.3) 0.004

Abbreviations: CCB—calcium channel blocker, CHD—coronary heart disease, CVD—cardiovascular disease, IQR—interquartile range, HDL-C—high density lipoprotein cholesterol, SD—standard deviation.