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. 2016 Jun 1;7:145. doi: 10.3389/fphar.2016.00145

FIGURE 2.

FIGURE 2

Effects of rhEndostatin on osteoclast-like cell formation treated for different time periods. (A) Schematic of the experimental design for the in vitro experiments. BMMs were cultured in the presence of M-CSF and RANKL for 5 days, and rhEndostatin (50 mM) was added to the BMM cultures at the indicated days. (B) The number of TRAP-positive multi-nucleated cells were counted. The data are presented as percentages relative to the vehicle-treated control group. ∗∗P < 0.01 compared with the vehicle-treated control.