Table 1.
Age, years | Perioda | Datesb | Colonization |
No. of IPD Cases | Reference No.c | |||
---|---|---|---|---|---|---|---|---|
No. of Participants | Total No. of Swabs | No. of Positive Swabs | % | |||||
<7 | ||||||||
1 | June 1995–June 2000 | 411 | 1,077 | 684 | 63.5 | 252 | 20 | |
2 | July 2000–June 2004 | 1,914 | 1,918 | 1,185 | 61.8 | 117 | 19 | |
3 | July 2004–June 2010 | 549 | 3,329 | 1,835 | 55.1 | 132 | 18 | |
4 | July 2010–December 2012 | 3,259 | 3,259 | 1,686 | 51.7 | 22 | ||
18–39 | ||||||||
1 | June 1995–June 2000 | N/A | N/A | N/A | N/A | 116 | N/A | |
2 | July 2000–June 2004 | 1,494 | 1,507 | 180 | 11.9 | 56 | 19 | |
3 | July 2004–June 2010 | 373 | 2,199 | 240 | 10.9 | 96 | 18 | |
4 | July 2010–December 2012 | 2,307 | 2,307 | 277 | 12.0 | 24 | N/A | |
≥40 | ||||||||
1 | June 1995–June 2000 | N/A | N/A | N/A | N/A | 311 | N/A | |
2 | July 2000–June 2004 | 500 | 504 | 48 | 9.5 | 205 | 19 | |
3 | July 2004–June 2010 | 67 | 427 | 41 | 9.6 | 418 | 18 | |
4 | July 2010–December 2012 | 399 | 399 | 37 | 9.3 | 110 | N/A |
Abbreviations: IPD, invasive pneumococcal disease; N/A, not applicable.
a Carriage data were collected as part of a randomized controlled trial, and only data from the control group (who did not receive pneumococcal conjugate vaccine serotype 7) were included in this analysis.
b Date ranges denote when the disease isolates were collected. Carriage isolates were collected over shorter periods of time within these windows (1998–2000, 2001–2002, 2006–2008, and 2010–2012).
c Carriage data from period 4 are unpublished.