Table 4.
Categorical Exposure-Response Relationships Between Any Color Vision Defect and Cumulative Exposure to Nonhexane Solvents, Hexane, and Hexane in the Presence of Acetone (Log-Binomial Regression) Among Participants Completing the Lanthony Desaturated D-15 Panel Test, Bay Area Solvent Study, 2007–2013
| Model and Exposure Category | All Participants |
Participants Aged ≤50 Years |
||||
|---|---|---|---|---|---|---|
| No. of Cases | PR | 95% CI | No. of Cases | PR | 95% CI | |
| Nonhexane solvents | ||||||
| Exposure, mg/m3-yeara | ||||||
| 0–670.9 | 236 | 1.00 | Referent | 88 | 1.00 | Referent |
| >670.9–1,364.3 | 45 | 1.19 | 0.85, 1.65 | 19 | 1.42 | 0.83, 2.43 |
| >1,364.3–2,470.7 | 57 | 1.18 | 0.85, 1.64 | 24 | 1.73 | 1.02, 2.94 |
| >2,470.7 | 62 | 1.28 | 0.93, 1.76 | 27 | 1.72 | 0.97, 3.08 |
| Age, years | 72 | 1.04 | 1.02, 1.06 | 18 | 1.04 | 0.99, 1.09 |
| Hexane | ||||||
| Exposure, mg/m3-yeara | ||||||
| Unexposed to hexane | 236 | 1.00 | Referent | 88 | 1.00 | Referent |
| >0–33.7 | 125 | 0.81 | 0.62, 1.05 | 35 | 1.01 | 0.64, 1.58 |
| >33.7 | 56 | 0.82 | 0.63, 1.07 | 24 | 1.14 | 0.75, 1.74 |
| Age, years | 55 | 1.04 | 1.02, 1.06 | 29 | 1.06 | 1.01, 1.10 |
| Hexane + acetone | ||||||
| Exposure, mg/m3-yearb | ||||||
| Unexposed to hexane | 219 | 1.00 | Referent | 79 | 1.00 | Referent |
| >0–17.1 | 125 | 0.77 | 0.58, 1.04 | 35 | 1.05 | 0.66, 1.67 |
| >17.1 | 41 | 0.94 | 0.73, 1.22 | 21 | 1.33 | 0.86, 2.06 |
| Age, years | 53 | 1.04 | 1.02, 1.06 | 23 | 1.06 | 1.02, 1.11 |
Abbreviations: CI, confidence interval; PR, prevalence ratio.
a There were 754 total participants and 359 participants aged ≤50 years.
b There were 669 total participants and 310 participants aged ≤50 years.