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. 2016 May 26;18(5):307–316. doi: 10.1016/j.neo.2016.04.001

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Inflammatory cytokines in chronically Salmonella-infected colon in mice. (A) Immunocyte infiltration in control and infected colon cancer tissue by immunohistochemistry/immunofluorescence. (B) Quantitation of CD3-, CD4-, CD14-, CD45-, and CD11b-positive cells in tumors or control mucosa/high-power field. *P < .05. (C) Serum IL-6 versus tissue levels of IL-6 45 weeks postinfection. n = 4 mice/group. Serum IL-6 at indicated time points. (D) IL17 mRNA level was increased in the AvrA+-infected colon group. n = 4 mice/group.