Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The working model of STAT3 and AvrA interaction in chronic intestinal Salmonella infected in colon cancer. Salmonella effector AvrA is secreted through the Salmonella Type Three Secretion System and persistently upregulates the STAT-3 signaling pathway. Several STAT3 target genes were upregulated by Salmonella expressing AvrA. β-catenin–STAT3 may co-regulate one another in a positive feedback loop, thus promoting proliferation and intestinal tumorigenesis.
