Table 4.
Baseline | 50% | 75% | 100% | 1 h | 3 h | 6 h | 24 h | ||
---|---|---|---|---|---|---|---|---|---|
Haemodynamics | |||||||||
Mean arterial blood pressure (mmHg) | 90 min | 94 ± 2 | 92 ± 2 | 92 ± 2 | 92 ± 2 | 93 ± 2 | 95 ± 3 | 95 ± 3 | 94 ± 3 |
120 min | 93 ± 3 | 93 ± 3 | 93 ± 3 | 93 ± 3 | 92 ± 2 | 94 ± 3 | 93 ± 3 | 95 ± 3 | |
Cardiac output (l min−1) | 90 min | 12.0 ± 1.1 | 12.6 ± 1.0 | 12.5 ± 1.2 | 13.5 ± 1.2 | 12.9 ± 1.1 | 13.0 ± 0.9 | 12.7 ± 1.0 | 11.8 ± 0.7 |
120 min | 11.7 ± 0.8 | 11.8 ± 0.7 | 11.1 ± 0.6 | 11.9 ± 0.8 | 12.2 ± 0.8 | 12.6 ± 0.9 | 12.4 ± 0.8 | 11.5 ± 0.8 | |
Systemic vascular resistance (mmHg min l−1) | 90 min | 8.6 ± 0.9 | 7.8 ± 0.8 | 7.9 ± 0.8 | 8.0 ± 0.9 | 7.8 ± 0.8 | 7.7 ± 0.6 | 8.0 ± 0.9 | 8.4 ± 0.7 |
120 min | 8.3 ± 0.7 | 8.2 ± 0.5 | 8.6 ± 0.6 | 8.1 ± 0.6 | 8.0 ± 0.8 | 7.8 ± 0.7 | 7.8 ± 0.6 | 8.6 ± 0.8 | |
Intracardiac pressure (E/E') | 90 min | 6.3 ± 0.4 | 6.3 ± 0.4 | 6.1 ± 0.4 | 6.0 ± 0.3 | 6.0 ± 0.5 | 6.2 ± 0.4 | 6.4 ± 0.3 | 6.5 ± 0.4 |
120 min | 6.6 ± 0.4 | 6.5 ± 0.5 | 6.4 ± 0.5 | 6.2 ± 0.3 | 6.4 ± 0.4 | 6.2 ± 0.4 | 6.1 ± 0.3 | 6.3 ± 0.4 | |
Conventional echocardiography | |||||||||
LV end diastolic volume (ml) | 90 min | 151 ± 10 | 145 ± 8 | 145 ± 9 | 148 ± 9 | 144 ± 9 | 148 ± 9 | 145 ± 9 | 151 ± 8 |
120 min | 148 ± 9 | 151 ± 9 | 147 ± 9 | 150 ± 8 | 149 ± 9 | 146 ± 8 | 145 ± 8 | 146 ± 8 | |
LV end systolic volume (ml) | 90 min | 42 ± 3 | 45 ± 4 | 45 ± 5 | 47 ± 4 | 45 ± 3 | 46 ± 4 | 43 ± 4 | 46 ± 3 |
120 min | 43 ± 3 | 49 ± 5 | 47 ± 4 | 45 ± 4 | 47 ± 4 | 45 ± 3 | 47 ± 4 | 45 ± 4 | |
LV stroke volume (ml) | 90 min | 130 ± 9 | 115 ± 8* | 113 ± 8* | 117 ± 7* | 114 ± 8* | 120 ± 7* | 125 ± 8 | 123 ± 7 |
120 min | 128 ± 8 | 122 ± 6 | 117 ± 6* | 115 ± 7* | 120 ± 7 | 124 ± 6 | 123 ± 8 | 129 ± 8 | |
RV fractional area change (%) | 90 min | 57.4 ± 1.2 | 52.5 ± 1.8* | 52.8 ± 1.6* | 53.3 ± 1.7* | 52.1 ± 1.9* | 54.0 ± 1.7* | 51.7 ± 1.4* | 53.4 ± 1.9 |
120 min | 56.9 ± 1.1 | 52.6 ± 1.6* | 52.8 ± 1.8* | 54.4 ± 1.8* | 52.4 ± 2.2* | 54.4 ± 1.6* | 51.9 ± 1.3* | 53.9 ± 1.7 |
Data are the mean ± SEM. *Significantly different from baseline (P < 0.05). †Significantly different from 90 min (P < 0.05).