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. 2016 Apr 21;11(6):3597–3604. doi: 10.3892/ol.2016.4489

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — The effect of silencing GEN1 on apoptosis in SKBR3 and MCF-7 cells. (A) The apoptosis of SKBR3 cells was observed under a fluorescence microscope (magnification, ×200). (B) The apoptosis of SKBR3 cells was detected by flow cytometry. (C) The apoptosis of MCF-7 was observed under a fluorescence microscope (magnification, ×200). (D) The apoptosis of MCF-7 cells was detected by flow cytometry. GEN1, flap endonuclease GEN homolog 1; sh-Ctrl; control short hairpin RNA; sh-GEN1, GEN1 short hairpin RNA; PI, propidium iodide.