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. 2016 Mar 30;4(6):947–953. doi: 10.3892/mco.2016.841

Table IV.

Clinical outcomes of patients who responded and those who did not respond to metronomic chemotherapy.

Outcomes Responders Non-responders P-value
Response rate, % 100     0
Clinical benefit rate, % 100 47.1 0.0002
Disease control rate, % 100 58.8 0.0023
Median TTF, months 33     9 0.00002
Median TTP, months 41   11 0.000008
Median OS, months Not reached   30 0.00002
Median OS from MBC, months Not reached   40 0.0033

Bold print indicates statistical significance. TTF, time-to-treatment failure; TTP, time-to-progression; OS, overall survival; MBC, metastatic breast cancer.