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Cell proliferation and hydroxyproline secretion were promoted by coxsackievirus B3 (CVB3) in neonatal rat cardiac fibroblasts. The fibroblasts were infected with CVB3 for 24, 48 and 72 h, and then (A) 5-bromo-2′-deoxyuridine (BrdU) incorporation and (B) hydroxyproline secretion were assessed. Data are presented as the mean ± standard error of the mean (n=3). *P<0.05 vs. the control group at the same time point.
