Table II.
Hypogonadism (n=100) | |||||
---|---|---|---|---|---|
Characteristics | Patients, n | Negative (n=33), n (%) | Positive (n=67), n (%) | χ2 test | P-value |
Age, years | 5.49 | 0.019a | |||
≤14 | 66 | 27 (40.9) | 39 (59.1) | ||
>14 | 34 | 6 (17.6) | 28 (82.4) | ||
Gender | 0.01 | 0.93 | |||
Male | 54 | 18 (33.3) | 36 (66.7) | ||
Female | 46 | 15 (32.6) | 31 (67.4) | ||
Age of start transfusion, months | 14.81 | <0.001b | |||
≤9 | 68 | 14 (20.6) | 54 (79.4) | ||
>9 | 32 | 19 (59.4) | 13 (40.6) | ||
Frequency of transfusion, weeks | 19.16 | <0.001b | |||
Every 2–3 | 43 | 4 (9.3) | 39 (90.7) | ||
Every 4–5 | 57 | 29 (50.9) | 28 (49.1) | ||
Age of start chelation, years | 28.20 | <0.001b | |||
≤3 | 73 | 13 (17.8) | 60 (82.2) | ||
>3 | 27 | 20 (74.1) | 7 (25.9) | ||
Type of chelators | 5.70 | 0.12 | |||
DFX | 19 | 9 (47.4) | 10 (52.6) | ||
DFP | 40 | 13 (32.5) | 27 (67.5) | ||
DFO | 31 | 6 (19.4) | 25 (80.6) | ||
DFO+DFP | 10 | 5 (50.0) | 5 (50.0) | ||
Compliance, % | 9.69 | 0.0018a | |||
<60 | 69 | 16 (23.2) | 53 (76.8) | ||
≥60 | 31 | 17 (54.8) | 14 (45.2) | ||
Mean serum ferritin level ± SD (range), ng/ml | 2,207.2±755.9 (836–5,000) | 4,252.4±1,824.1 (1,626–8,500) | 6.12 | <0.001b |
P<0.05
P<0.001. DFX, deferasirox; DFP, deferiprone; DFO, desferrioxamine; SD, standard deviation.