Table V.
Association between hypoparathyroidism and each of the demographic, transfusion, chelation characteristics, compliance and serum ferritin level.
| Hypoparathyroidism (n=100) | |||||
|---|---|---|---|---|---|
| Characteristics | Patients, n | Negative (n=93), n (%) | Positive (n=7), n (%) | χ2 test | P-value |
| Age, years | 4.65 | 0.03a | |||
| ≤14 | 66 | 64 (97.0) | 2 (3.0) | ||
| >14 | 34 | 29 (85.3) | 5 (14.7) | ||
| Gender | 0.05 | 0.82 | |||
| Male | 54 | 50 (92.6) | 4 (7.4) | ||
| Female | 46 | 43 (93.5) | 3 (6.5) | ||
| Age of start transfusion, months | 0.39 | 0.53 | |||
| ≤9 | 68 | 62 (91.2) | 6 (8.8) | ||
| >9 | 32 | 31 (96.9) | 1 (3.1) | ||
| Frequency of transfusion, weeks | 1.39 | 0.23 | |||
| Every 2–3 | 43 | 38 (88.4) | 5 (11.6) | ||
| Every 4–5 | 57 | 55 (96.5) | 2 (3.5) | ||
| Age of start chelation, years | 0.12 | 0.73 | |||
| ≤3 years | 73 | 67 (91.8) | 6 (8.2) | ||
| >3 years | 27 | 26 (96.8) | 1 (3.7) | ||
| Type of chelators | 3.08 | 0.37 | |||
| DFX | 19 | 19 (100.0) | 0 (0.0) | ||
| DFP | 40 | 36 (90.0) | 4 (10.0) | ||
| DFO | 31 | 28 (90.0) | 3 (9.7) | ||
| DFO+DFP | 10 | 10 (100.0) | 0 (0.0) | ||
| Compliance, % | 2.00 | 0.15 | |||
| <60 | 69 | 62 (89.9) | 7 (10.1) | ||
| ≥60 | 31 | 31 (100.0) | 0 (0.0) | ||
| Mean serum ferritin level ± SD (range), ng/ml | 3,398.7±1,591.2 (836–7,830) | 5,952.6±3,022.6 (1,026–8,500) | 3.80 | <0.001b | |
a
P<0.05
b
P<0.001. DFX, deferasirox; DFP, deferiprone; DFO, desferrioxamine; SD, standard deviation.