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. 2016 Jun 1;6:26965. doi: 10.1038/srep26965

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Copyright © 2016, Macmillan Publishers Limited

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Hippocampi from 3, 12 and 24 month-old 3XTg-AD mice were co-stained with FEZ1 and Kinesin-1. Aggregates containing both proteins could already be observed at 3 months of age and progressively increase with aging and disease progression. Scale bars for the top 3 panels indicate 20 μm. Scale bar for the bottom panel indicates 10 μm.