Table 3. Statistical analysis of the genotype data between cases and controls.
| Genotype/Allele | A499V (C/T) | K939Q(A/C) | |
|---|---|---|---|
| OR (95%CI), p-value | OR (95%CI), p-value | ||
| Overall | 11 vs 12 | 1.69(1.1–2.60), 0.017* | 1.06(0.69–1.63), 0.79 |
| 11 vs 22 | 1.96(1.20–3.19), 0.007* | 0.84(0.52–1.36), 0.47 | |
| 12vs 22 | 1.16(0.75–1.79), 0.51 | 0.79(0.51–1.21), 0.28 | |
| 11 vs 12 + 22 | 1.78(1.19–2.66), 0.005* | 0.97(0.65–1.45), 0.89 | |
| 22 vs11 + 12 | 1.41(0.94–2.11), 0.095 | 0.81(0.54–1.20), 0.29 | |
| Non-smokers | 11 vs 12 | 1.12(0.55–2.31), 0.75 | 0.97(0.46–2.06), 0.92 |
| 11 vs 22 | 0.92(0.35–2.40), 0.816 | 0.81(0.35–1.87), 0.63 | |
| 12vs 22 | 0.82(0.35–1.90), 0.64 | 0.84(0.41–1.71), 0.63 | |
| 11 vs 12 + 22 | 1.08(0.54–2.17), 0.84 | 0.91(0.45–1.84), 0.79 | |
| 22 vs11 + 12 | 0.85(0.38–1.91), 0.69 | 0.83(0.43–1.62), 0.59 | |
| Smokers | 11 vs 12 | 1.51(0.81–2.81), 0.197 | 1.02(0.58–1.79), 1.00 |
| 11 vs 22 | 3.36(1.81–6.26), < 0.0001* | 0.78(0.41–1.48), 0.45 | |
| 12vs 22 | 2.23(1.27–3.92), 0.005* | 0.77(0.43–1.37), 0.37 | |
| 11 vs 12 + 22 | 2.23(1.28–3.87), 0.004* | 0.92(0.54–1.55), 0.76 | |
| 22 vs11 + 12 | 2.67(1.62–4.40), < 0.0001* | 0.77(0.45–1.32), 0.35 | |
| Tobacco non-chewers | 11 vs 12 | 0.92(0.45–1.91), 0.82 | 0.96(0.45–2.07), 0.92 |
| 11 vs 22 | 1.40(0.56–3.50), 0.47 | 0.85(0.37–1.92), 0.69 | |
| 12vs 22 | 1.52(0.67–3.44), 0.32 | 0.88(0.42–1.82), 0.73 | |
| 11 vs 12 + 22 | 1.04(0.52–2.08), 0.92 | 0.91(0.45–1.84), 0.81 | |
| 22 vs11 + 12 | 1.48(0.68–3.22) 0.33 | 0.87(0.44–1.69), 0.68 | |
| Tobacco-chewers | 11 vs 12 | 2.30(1.31–4.03), 0.003* | 1.14(0.67–1.95), 0.62 |
| 11 vs 22 | 2.56(1.39–4.70), 0.002* | 0.80(0.43–1.47), 0.47 | |
| 12vs 22 | 1.11(0.66–1.88), 0.69 | 0.70(0.40–1.20), 0.19 | |
| 11 vs 12 + 22 | 2.40(1.43–4.04), 0.0008* | 1.00(0.61–1.66), 1.00 | |
| 22 vs11 + 12 | 1.53(0.94–2.48), 0.086 | 0.73(0.44–1.22), 0.23 |