Table I.
Patient characteristics.
| Characteristic | No. of patients |
|---|---|
| Gender | |
| Female | 15 |
| Male | 27 |
| Median age (range), years | 61 (51–78) |
| Treatment for cisplatin-based regimen | |
| Pre-operative | 3 |
| Post-operative | 12 |
| Metastatic | 27 |
| Metastatic sites at the initiation of second-line therapy | |
| Lymph node | 31 |
| Lung | 24 |
| Liver | 13 |
| CNS | 1 |
| Bone | 23 |
| Biological parameters at the initiation of second-line therapy | |
| Hemoglobin (gr/dl) | 10.7 |
| Platelets (/mm3) | 311682 |
| Neutrophil/lymphocyte ratio | 7.814 |
| Albumin (gr/l) | 3.594 |
| Lactate dehydrogenase (IU/l) | 537 |
| Creatinine (mg/dl) | 1.35 |
| Alkaline phosphatase (ALP) IU/l | 277 |
| C-reactive protein (mg/dl) | 39.27 |