Transwell assay was performed to determine the cell migratory capacity of WM451 cells transfected with miR-138 mimics or HIF-1α siRNA, respectively (stain, crystal violet; magnification, ×200). Control: WM451 cells without any transfection. **P<0.01 vs. control. miR, microRNA; HIF-1α, hypoxia-inducible factor-1alpha; siRNA, small interfering RNA.